Well after 9 years of pain & suffering I am finally going tomorrow for final approval to start Biologics. I have RA in 36 joints with the most severity being wrists and hands.

Has anyone tried more than one Biologic? Which one has the least side effects? Any recommendations on which one is better? I am leaning towards Enbrel.

Over the last 2 years I have gained 60 pounds and am now a whopping 210 pounds. Because of the Arthiritis in my feet, knees, ankles, wrists, shoulders and hands I have found it nearly impossible to exercise with any amount of repetition without ending in severe pain the following day. I know the weight gain is making the pain worse but I am stuck in a viscious circle. Any ideas on weight loss solutions???